Infinium Global Screening Array-24 Kit

这种新一代基因分型芯片为群体遗传学、药物基因组学研究和精准医学研究提供了一种可扩展且经济的解决方案。 阅读更多...
选择产品
What size kit do I need?
Fixed Content

Infinium Global Screening Array-24 v3.0 Kit (48 Samples)

20030770

Infinium Global Screening Array-24 v3.0 Kit (288 Samples)

20030771

Infinium Global Screening Array-24 v3.0 Kit (1152 Samples)

20030772


Add-On Content

Infinium Global Screening Array-24+ v3.0 Kit (48 Samples)

20030773

Infinium Global Screening Array-24+ v3.0 Kit (288 Samples)

20030774

Infinium Global Screening Array-24+ v3.0 Kit (1152 Samples)

20030775

Infinium HTSE GSA-24+ v3.0(4,608 Spl)

20034098

Infinium HTSE GSA-24+ v3.0(23,040 Spl)

20034099


Services

Infinium Training

20015273

产品特色

Global Content

The Infinium Global Screening Array-24 BeadChip combines multi-ethnic genome-wide content, curated clinical research variants, and quality control (QC) markers for precision medicine research.

The genome-wide content was selected for high imputation accuracy at minor allele frequencies of >1% across all 26 1000 Genomes Project populations. The clinical research content includes variants with established disease associations, relevant pharmacogenomics markers, and curated exonic content based on ClinVar, NHGRI, PharmGKB, and ExAC databases. QC content enables sample identification and tracking for large-scale genomics and screening applications.

Widespread Adoption

With over 15 million samples worth of BeadChips sold, the Global Screening Array's global adoption provides a network of human disease researchers, healthcare networks, consumer genomics companies, and genomic service providers to help power discovery.

Robust Assay and High-Throughput Workflow

The array supports genotyping and CNV calling for sample types including saliva, blood, and buccal swabs. The format allows processing of hundreds to thousands of samples per week with a 3-day workflow for population-scale studies.

Broad Clinical Research Applications

The array provides a genomic tool for clinical research applications including disease risk profiling studies, pharmacogenomics research, wellness characterization, and complex disease discovery.

Version 3 of the Global Screening Array leverages the most up to date and relevant clinical research screening markers derived from ClinVar, CPIC, and PharmGKB.

As leading databases such as ClinVar continue to rapidly add new variants, Illumina is dedicated to ensuring the variants interrogated on the GSA remain updated and relevant. The launch of the Infinium GSA-24 v3.0 BeadChip includes an update of key variants found in ACMG 59 genes. A growing number of precision medicine research initiatives around the world are leveraging these variants to screen populations for the following applications:

  • Studying disease risk by investigating the role of ClinVar designated "Pathogenic" and "Likely Pathogenic" variants in the likelihood of developing a phenotype and the frequency of such alleles within a given population.
  • Stratifying samples to allow for cost savings by enabling a program to focus more elaborate testing on select samples that are flagged as having interesting or suspicious findings.
  • Incentivizing participation and providing value to participants through return of results, boosting project sample sizes and discovery power.

View Manifest (Array Content) Files

经常一并购买

规格

产品比较

Infinium Global Screening Array-24 Kit Infinium Multi-Ethnic Global-8 Kit (Discontinued) Infinium Omni2.5-8 Kit
技术 芯片 芯片 芯片
标记物数量 固定标记物:约654,027
定制标记物扩展容量可达 50,000
固定标记物: 1,779,819
定制标记物扩展容量:多达245,000个
固定标记物:约2,381,000, 定制标记物扩展容量:无
样本数量 每张芯片24个样本 每张芯片8个样本 每张芯片8个样本
样本通量 每台iScan系统可处理约5760个样本/周(通量和扫描时间可能因实验室和系统配置而异。) 每台iScan系统最多可处理约1728个样本/周(通量和扫描时间可能因实验室和系统配置而异。) 每台iScan系统可处理约1728个样本/周(最大通量和扫描时间可能因实验室和系统配置而异。)
核酸类型 DNA DNA DNA
物种类别 人类 人类 人类
说明 经济实用的新一代基因分型芯片,通过结合高度优化的多种族全基因组内容、精选的临床研究变异和QC标记物支持群体规模的遗传学、转化研究、变异筛查研究和精准医疗研究。 这款多种族芯片包含来自多个资源渠道的内容,让研究人员能够在5个最常作为研究对象的超群体中检测常见和罕见变异,以推断大量亚群中可能存在的变异。 8样本芯片具有高通量和优化的标签SNP内容,全面支持拷贝数变异应用,旨在提供高度可定制、信息量大的芯片用于研究不同的世界人口群体。

Method-Specific Workflow Example

 

Case Studies and Feature Articles

Scalable High-Throughput Array Enables Ethnic Chinese Genome Database Development
Scalable High-Throughput Array Enables Ethnic Chinese Genome Database Development

Fast Infinium array analysis and broad genome coverage support personal genetic testing services and database development.

Read Interivew
Bringing Meaning to Genetic Information
Bringing Meaning to Genetic Information

MyDNA recently began partnering with Illumina customers using the Global Screening Array and Asian Screening Array in their genetic test offerings.

Read Interview
Polygenic Risk Scores Could Become Useful Tools in the Physician's Toolbox
Polygenic Risk Scores Could Become Useful Tools in the Physician's Toolbox

Researchers perform large GWAS studies with the Global Screening Array to identify disease-associated DNA risk loci and develop PRSs for clinical validation.

Read Interview
Genetic Testing Services Gain a Presence in India

The Global Screening Array and iScan System are helping Mapmygenome bring consumer genomics to a rapidly growing Indian population.

Read Article
Genetic Testing Services Gain a Presence in India
基因panel和芯片查找工具

芯片是一种很有价值的变异检测工具。借助基因panel和芯片查找工具,您可以用基因组位置或变异ID搜索人类芯片,或查找其他物种的芯片。

寻找合适的panel
基因panel和芯片查找工具

相关产品

Infinium Global Diversity Array with Enhanced PGx

Infinium Global Diversity Array (GDA) with Enhanced PGx is the most comprehensive genotyping microarray on the market for pharmacogenomics research.


Infinium XT

Infinium XT is a comprehensive microarray solution that enables production-scale genotyping of up to 50,000 single or multi-species custom variants.


Infinium HTS iSelect Custom Beadchips

Interrogate virtually any target across any species to create a fully customized microarray tailored to your unique study needs.