全基因组基因分型简介
全基因组基因分型能提供整个基因组的概况，使全基因组范围内的发现和关联研究成为可能。利用高通量新一代测序（NGS）和芯片技术，研究人员可以更深入地了解基因组，从而探知遗传变异的功能性后果。
基于芯片的全基因组关联分析（GWAS）已成为识别全基因组范围内疾病相关性常用的方法。虽然全基因组芯片可以对每份样本检测超过400万个标记，但基于NGS的全基因组测序提供了一种更为全面的方法，可以逐一检测人类基因组中的32亿对碱基。每种技术在价格、数据分析和通量方面都具有其独特的优势，应根据具体的研究目标来选择。
全基因组基因分型的优势
- 提供全面的基因组视图
- 在全基因组范围内检测单核苷酸多态性（SNP）和其他变异
- 可以为今后的靶向研究鉴定潜在的致病性变异
- 最大限度地减少了内容限制，扩大了探索范围
Featured Genotyping Research
Genetics of COVID-19 Susceptibility
Illumina is providing sequencing for a UK-wide study led by Genomics England, designed to compare the genomes of severely and mildly ill COVID-19 patients.
Read ArticlePharmacogenomics and Cardiovascular Disease
Researchers use an Illumina array to identify responder genotypes in a cholesterol drug trial.
Read InterviewGenome-Wide Genotyping Studies in Hispanic Populations
A collaborative genotyping effort identifies disease-associated SNP markers prevalent in the Hispanic population.
Read InterviewNon-Human Whole-Genome Genotyping with Arrays
Illumina offers a comprehensive suite of genome-wide genotyping array products for non-human organisms. Find ready-to-use solutions for crops, livestock, and model organisms, or genotype any species with our custom array options.
Array and Library Prep Kit Selector
Find and compare non-human whole-genome genotyping arrays with this easy-to-use tool.
Find Non-Human ArraysAll Non-Human Genotyping Kits
Access a wide variety of kits, including arrays, for genotyping non-human species such as crops, livestock, and model organisms.
See All Agrigenomics KitsCustom Genotyping
Design custom arrays for any species or population, including those not supported by standard products.
Learn MoreInfinium Global Screening Array
The Infinium Global Screening Array is a next-generation genotyping array for population-scale genetics, variant screening, and precision medicine research.
Learn More
为芯片增添新变异
利用NGS发现的新变异可用于设计完全定制的芯片，或作为附加内容添加到现有的全基因组基因分型芯片中，用于大样本筛查研究。您可以针对特定性状和/或感兴趣的基因，或针对标准panel不涉及的物种和种群，设计定制panel。
了解定制基因分型
Infinium Global Screening Array
The Infinium Global Screening Array is a next-generation genotyping array for population-scale genetics, variant screening, and precision medicine research.
Learn More相关解决方案
大规模基因分型
高通量芯片有助于实验室开展群体规模的基因分型研究，检测大规模群体中的常见遗传变异。深入了解高通量基因分型。
致病变异发现
快速筛查大量样本，发现与复杂疾病相关的致病变异。深入了解致病变异发现。
动植物基因分型
使用有助于育种决策的筛选和发现工具来提升作物和畜群的价值。深入了解动植物基因分型。
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Gene Panel and Array Finder
Identify sequencing panels or microarrays that target your genes of interest.