全基因组基因分型能提供整个基因组的概况,使全基因组范围内的发现和关联研究成为可能。利用高通量新一代测序(NGS)和芯片技术,研究人员可以更深入地了解基因组,从而探知遗传变异的功能性后果。
基于芯片的全基因组关联分析(GWAS)已成为识别全基因组范围内疾病相关性常用的方法。虽然全基因组芯片可以对每份样本检测超过400万个标记,但基于NGS的全基因组测序提供了一种更为全面的方法,可以逐一检测人类基因组中的32亿对碱基。每种技术在价格、数据分析和通量方面都具有其独特的优势,应根据具体的研究目标来选择。
Illumina is providing sequencing for a UK-wide study led by Genomics England, designed to compare the genomes of severely and mildly ill COVID-19 patients.
Read ArticleResearchers use an Illumina array to identify responder genotypes in a cholesterol drug trial.
Read InterviewA collaborative genotyping effort identifies disease-associated SNP markers prevalent in the Hispanic population.
Read InterviewIllumina offers a comprehensive suite of genome-wide genotyping array products for non-human organisms. Find ready-to-use solutions for crops, livestock, and model organisms, or genotype any species with our custom array options.
Find and compare non-human whole-genome genotyping arrays with this easy-to-use tool.
Find Non-Human ArraysAccess a wide variety of kits, including arrays, for genotyping non-human species such as crops, livestock, and model organisms.
See All Agrigenomics KitsDesign custom arrays for any species or population, including those not supported by standard products.
Learn More利用NGS发现的新变异可用于设计完全定制的芯片,或作为附加内容添加到现有的全基因组基因分型芯片中,用于大样本筛查研究。您可以针对特定性状和/或感兴趣的基因,或针对标准panel不涉及的物种和种群,设计定制panel。
了解定制基因分型高通量芯片有助于实验室开展群体规模的基因分型研究,检测大规模群体中的常见遗传变异。深入了解高通量基因分型。
快速筛查大量样本,发现与复杂疾病相关的致病变异。深入了解致病变异发现。
使用有助于育种决策的筛选和发现工具来提升作物和畜群的价值。深入了解动植物基因分型。