Skip to content

Phased测序

Scientists in lab

Introduction to Phased Sequencing

Historically, whole-genome sequencing generated a single consensus sequence without distinguishing between variants on homologous chromosomes. Phased sequencing, or genome phasing, addresses this limitation by identifying alleles on maternal and paternal chromosomes. This information is often important for understanding gene expression patterns for genetic disease research.

Phased测序的优势

新一代测序(NGS)可以进行全基因组phasing,而不依赖于三重分析或统计推断。 Phased测序可以鉴定单倍型来为复杂性状的研究提供信息,这些复杂的性状往往受到多个基因和等位基因的相互作用的影响。染色体上顺式或反式等位基因的破坏可以导致某些遗传性疾病,因此,phasing测序也能为遗传疾病研究提供有价值的信息。

Phasing测序能帮助研究人员:

  • 分析复合杂合变异
  • 测量等位基因特异性表达
  • 鉴定变异连锁
什么是phased测序?

了解基因组phasing的优势。

观看视频
产品选择和实验规划工具

寻找工具来协助您根据需要选择合适的产品并规划实验。

探索工具
产品选择和实验规划工具

人类全基因组phasing解决方案

10x Genomics Chromium Genome Library Prep Kit

提供全基因组范围的长片段信息,可利用NGS技术进行变异检出、phasing和广泛的基因组结构鉴定。

了解更多
BaseSpace Sequence Hub

Illumina基因组学计算环境,为NGS数据分析和管理提供了专业的应用程序。

了解更多
希望收到有关基因组学分析技术的快讯、案例研究和信息?

请输入您的电子邮箱地址。

Additional Resources

Flexible High-Throughput Sequencer
Flexible High-Throughput Sequencer

The NovaSeq System offers scalable throughput and flexibility for virtually any genome, sequencing method, and scale of project.

Accurate Long-Read Sequencing Technology
Accurate Long-Read Sequencing Technology

Illumina technology assembles synthetic long reads from shorter reads to provide more information while maintaining accuracy.