Targeted methylation sequencing (Methyl-Seq) offers a balanced, cost-effective choice between whole-genome bisulfite sequencing and methylation arrays that can support both screening and biomarker discovery study objectives.1 TruSeq Methyl Capture EPIC Library Prep supports researchers seeking a deeper understanding of the role of methylation in gene regulation.
Comprehensive methylation-site content: Offers significantly higher coverage of emerging epigenetic regions of interest compared to other Methyl-Seq kits currently on the market (See Supporting Data section, Epigenetic Regions Covered).
Maximize discovery power, minimize cost: Efficiently query differentially methylated bases to conserve research dollars.
Convenient kit configuration: Includes bisulfite conversion, library prep, target enrichment, and purification reagents in a single kit for hassle-free ordering.
User-friendly data analysis: Analyze sequence data in BaseSpace Sequence Hub with methylation apps designed for biologists.
TruSeq Methyl Capture EPIC Library Prep Kit | Infinium MethylationEPIC Kit | |
---|---|---|
Content Specifications | Targets over 3.3 million CpGs. Interrogates biologically important methylome targets. | Targets 850,000 CpGs. Quantitatively interrogates selected methylation sites across the genome. |
Description | Focused interrogation of a set of methylome targets for a balanced, cost-effective option that can support both screening studies and biomarker discovery research objectives. | Quantitative interrogation of selected methylation sites across the genome, offering high-throughput research capabilities at a minimal cost per sample. |
Input Quantity | 500 ng human genomic DNA | 250 ng DNA |
Method | Methylation Sequencing, 靶向DNA测序 | Methylation Array |
Number of Samples | Up to 12-plex | 8 samples per array |
Species Category | 人类 | 人类 |
Technology | 测序 | Microarray |