| System: | iScan, BeadArray Reader, HiScanSQ |
|---|---|
| Technology: | BeadArray |
| Assay: | GoldenGate Methylation Assay |
| Applications: | Array-Based Methylation Analysis, Custom Low- to Mid-plex Methylation Analysis |
| Species: | Any |
| Contents: | A single Universal Array Matrix that can process 96 samples with up to 1,536 assay/samples for methylation |
Please note that this product is in the process of being discontinued. It will be available while supplies last or until Spring 2010, whichever comes first.
Illumina's GoldenGate Methylation Assay combines high sample throughput, high multiplexing, and single-site CpG resolution for DNA methylation profiling. The Assay can be used to simultaneously analyze the methylation status of up to 1,536 independent CpG sties per assay.
The 96-sample Universal Array Matrix (SAM) is used in the hybridization step of the GoldenGate Methylation Assay. Instead of gene-specific sequences, it contains universal sequences or addresses that hybridize to complementary sequences in the prepared sample.
The GoldenGate Methylation Assay requires use of a DNA Activation Kit, GoldenGate Assay Kit, Oligo Pool for Methylation Assay (OMA), and Methylation Universal Array.
For methylation profiling studies requiring low- to mid-plex analysis, Illumina provides a customized solution that allows researchers to target CpG loci within genes or regions of interest. With the proven GoldenGate Methylation Assay, customized probes can be easily developed for virtually any experimental design.
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