| System: | iScan, iScanSQ, HiScanSQ |
|---|---|
| Technology: | BeadArray |
| Assay: | Infinium DNA Analysis Assay |
| Applications: | Cytogenetic Analysis, Whole-Genome Genotyping and Copy Number Analysis |
| Species: | Human |
The Omni1S BeadChip is an integral part of the 2010 GWAS product roadmap , which provides researchers favorable pricing and the fastest access to new variants identified by the 1000 Genomes Project. Researchers can begin genome-wide association studies immediately and add additional markers on supplemental arrays as they become available. For those interested in the 2010 GWAS product roadmap, Illumina has developed Infinium Multi-Use Sample Preparation kits. These kits require only a single sample amplification, which can be stored and used on supplemental roadmap arrays as they become available.
2010 GWAS Roadmap
| Infinium HD BeadChips | Markers per Sample |
|---|---|
| Number of Markers* | ~1.25 million |
| Samples per BeadChip | 8 |
| DNA Requirement | 200ng |
| Assay | Infinium HD |
| Instrument | iScan or HiScanSQ |
| Scan Ttime per Sample |
~ 7.5 minutes |
*Estimated, based on pre-release marker list
Genome-wide association studies (GWAS) map genetic variation across human populations to identify variants associated with human disease. Infinium HD BeadChips offer GWAS researchers the flexibility to profile samples with 300,000 to 1.2 million markers in high-throughput format, and deliver dense genome-wide coverage with the most up-to-date content available from the scientific community. Strategically selected probes provide sensitive copy number variation analysis and target high-value regions of the genome associated with disease.
More...Structural variability is a substantial source of genetic variation that has a major influence on phenotypic variation. Cytogenetic analysis allows researchers to profile chromosomal aberrations such as amplifications, deletions, rearrangements, point mutations, copy number changes, and copy-neutral loss of heterozygosity (LOH) events.
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