Human660W-Quad v1 DNA Analysis BeadChip Kits

The Human660W-Quad BeadChip offers comprehensive genomic coverage across many populations and the majority of known variation in regions of the genome, based on HapMap release 24 data. The broad, evenly spaced whole-genome marker set provides high genomic coverage for powerful genome-wide association studies. The entire panel of nearly 660,000 markers provides exceptional identification of known and novel structural variants.

The Human660W-Quad BeadChip was built on the HumanHap550 BeadChip. For powerful CNV and cytogenetic analysis, the dense backbone content is combined with an additional 100,000 markers that are highly informative for analyzing common CNV regions. These markers specifically target regions of common copy number variation that were recurrently identified in a high-density screen for CNVs that occur in two or more HapMap samples.

These BeadChips were developed in collaboration with researchers at The Centre for Applied Genomics, Hospital for Sick Children, Toronto, the Wellcome Trust Sanger Institute, and Harvard Medical School/Brigham and Women's Hospital.

• The convenient quad-sample format enables simultaneous processing of four samples at a time, increasing sample throughput and decreasing experimental variability
• The Human660W-Quad BeadChip offers the ability to assay limited sample resources, down to 200 ng DNA per sample
• Process samples using the single-tube, PCR-free Infinium HD Assay
• Add up to 60,800 SNPs of choice with the semi-custom Human550-Quad+ BeadChip